Sabrina founds the WICCA club explicitly named Women’s Intersectional Cultural and Creative Association to combat bullying and patriarchy at Baxter High, directly tying into critiques of toxic masculinity and male authority in both the mortal and witch worlds. The show centers Sabrina's reluctance to sign the Book of the Beast as resistance to patriarchal witch society, with creator Roberto Aguirre-Sacasa and star Kiernan Shipka describing her as a “woke witch” challenging male-dominated structures. Susie Putnam’s storyline follows a genderqueer journey with bullying for androgynous presentation and identity exploration, played by non-binary actor Lachlan Watson; Ambrose Spellman is portrayed as pansexual by Black actor Chance Perdomo in a role adapted with explicit queer framing.