The plot centers on a mysterious fog causing ability users worldwide to die by their own powers, leading the Armed Detective Agency to investigate villain Tatsuhiko Shibusawa (the Collector) with an uneasy alliance against the Port Mafia. Core themes include identity and power (abilities defining or constraining characters), trauma and self-acceptance (protagonist Atsushi Nakajima confronting his orphanage past and tiger ability), and alliances/sacrifice, all resolved through battles and personal resolve rather than external social frameworks.

This approach follows traditional Japanese anime storytelling with supernatural powers and literary author-inspired characters, where personal trauma arcs serve as the emotional driver. Creator Kafka Asagiri's intent emphasizes entertaining complex plots and encouraging literature engagement, with no activist messaging or DEI mandates evident in production or content. There is no race or gender-swapping of established characters, no overt LGBTQ+ or identity politics representation as focal points, and an all-Japanese voice cast that fits the source material. These elements keep the focus on character-driven supernatural conflicts and alliances without injecting contemporary political frameworks, resulting in a low woke score.