Its most prominent progressive element is companion Parvati Holcomb, an asexual biromantic character whose loyalty quest revolves around helping her pursue and navigate a romantic relationship with female engineer Junlei Tennyson; the game explicitly explores her asexuality, anxieties, and identity in dialogue without treating it as a twist or joke. Developers at Obsidian intentionally included diverse casting and representation while enforcing a rule against in-world racial or gender discrimination to isolate class critique, as stated by co-producer Tim Cain.

Character creation uses standard male/female options with no pronoun selection or body-type swaps. No established characters were altered for diversity, and player romances with companions are absent.

Reception shows solid critic (Metacritic 85) and user (7.8) scores with no major backlash tied to ideology. These elements make LGBTQ+ representation noticeable and central to one major companion arc but secondary to the core premise of anti-corporate satire and player-driven RPG choices.