The story follows Alice Liddell's personal confrontation with childhood trauma from a family fire later revealed as murder by psychiatrist Dr. Angus Bumby, her time in an asylum, and the threat of the Infernal Train to a corrupted Wonderland populated by figures such as the Cheshire Cat, Mad Hatter, Caterpillar, and the Red Queen as an embodiment of her sister Lizzie. The narrative remains grounded in psychological horror and mystery resolution rather than any ideological premise, with no romance systems, character creation tools, pronoun mechanics, or identity exploration as central elements. Creator American McGee explicitly resisted external marketing pressures from EA to introduce sexualization or reframe Alice as a 'psycho killer,' instead prioritizing a trauma-respectful approach that stayed faithful to the character's Victorian-era context and singular focus on processing grief and abuse.

The game shows a complete absence of DEI consultancy, activist themes, or contemporary identity politics, allowing the core experience to center on atmospheric storytelling and gameplay without modern ideological intrusions. This restraint keeps the title firmly outside progressive messaging trends while preserving its original artistic intent.